Intermittent Presumptive Treatment for Malaria

Intermittent Presumptive Treatment for Malaria

I ntermittent presumptive treatment (IPT) in pregnancy involves giving a curative treatment dose of an effective antimalarial drug at predefi ned intervals during pregnancy. IPT in pregnancy was fi rst introduced in areas of high malaria transmission as a measure to reduce the adverse impact of Plasmodium falciparum malaria based on trials showing that IPT could reduce anaemia in young children...

Editorial: presumptive anti-relapse treatment for malaria in military forces.

Sulfadoxine/Pyrimethamine Intermittent Preventive Treatment for Malaria during Pregnancy

For monitoring efficacy of sulfadoxine/pyrimethamine intermittent preventive treatment for malaria during pregnancy, data obtained from studies of children seemed inadequate. High prevalence of triple and quadruple mutants in the dihydropteroate synthase and dihydrofolate reductase genes of Plasmodium falciparum parasites contrasts with the efficacy of sulfadoxine/pyrimethamine in reducing low ...

Intermittent preventive treatment for malaria in infants: moving forward, cautiously.

The drug use strategy for malaria includes treatment for acute illness, chemoprophy-laxis, and, more recently, intermittent preventive treatment (IPT) of asymptomatic persons. Plasmodium falciparum resistance to antimalarial drugs is the major challenge to these interventions [1]. The study by Marks et al. [2] is the firs report of the appearance of highly resistant parasites after a single tre...

Intermittent Screening and Treatment versus Intermittent Preventive Treatment of Malaria in Pregnancy: Provider Knowledge and Acceptability

Malaria in pregnancy (MiP) is associated with increased risks of maternal and foetal complications. The WHO recommends a package of interventions including intermittent preventive treatment (IPT) with sulphadoxine-pyrimethamine (SP), insecticide-treated nets and effective case management. However, with increasing SP resistance, the effectiveness of SP-IPT has been questioned. Intermittent scree...